在过去的十年中，AI AID毒品发现（AIDD）的计算方法和数据集策划的繁荣发展。但是，现实世界中的药物数据集经常表现出高度不平衡的分布，这在很大程度上被当前的文献忽略了，但可能会严重损害机器学习应用程序的公平性和概括。在这一观察结果的激励下，我们介绍了Imdrug，这是一个全面的基准标准，其开源python库由4个不平衡设置，11个AI-Ready数据集，54个学习任务和16种为不平衡学习量身定制的基线算法。它为涵盖广泛的药物发现管道（例如分子建模，药物靶标相互作用和逆合合成）的问题和解决方案提供了可访问且可定制的测试床。我们通过新的评估指标进行广泛的实证研究，以证明现有算法在数据不平衡情况下无法解决药物和药物挑战。我们认为，Imdrug为未来的研究和发展开辟了途径，在AIDD和深度不平衡学习的交集中对现实世界中的挑战开辟了道路。

本文回顾了AIM 2022上压缩图像和视频超级分辨率的挑战。这项挑战包括两条曲目。轨道1的目标是压缩图像的超分辨率，轨迹〜2靶向压缩视频的超分辨率。在轨道1中，我们使用流行的数据集DIV2K作为培训，验证和测试集。在轨道2中，我们提出了LDV 3.0数据集，其中包含365个视频，包括LDV 2.0数据集（335个视频）和30个其他视频。在这一挑战中，有12支球队和2支球队分别提交了赛道1和赛道2的最终结果。所提出的方法和解决方案衡量了压缩图像和视频上超分辨率的最先进。提出的LDV 3.0数据集可在https://github.com/renyang-home/ldv_dataset上找到。此挑战的首页是在https://github.com/renyang-home/aim22_compresssr。

为了使婴儿脑瘫（CP）的早期医疗干预，早期诊断出脑损伤至关重要。尽管一般运动评估（GMA）在早期CP检测中显示出令人鼓舞的结果，但它很费力。大多数现有作品都以视频为输入，以对GMA自动化进行烦躁的动作（FMS）分类。这些方法需要对视频进行完整的观察，并且无法本地化包含正常FMS的视频帧。因此，我们提出了一种名为WO-GMA的新颖方法，以在弱监督的在线环境中执行FMS本地化。首先将婴儿体重点作为WO-GMA的输入提取。然后，WO-GMA执行本地时空提取，然后进行两个网络分支，以生成伪夹标签和模型在线操作。凭借剪辑级伪标签，动作建模分支学会以在线方式检测FMS。具有757个不同婴儿视频的数据集上的实验结果表明，WO-GMA可以获得最新的视频级别分类和Cliplevel检测结果。此外，仅需要前20％的视频持续时间才能获得与完全观察到的分类结果，这意味着FMS诊断时间大大缩短了。代码可在以下网址获得：https：//github.com/scofiedluo/wo-gma。

一对一的匹配是DETR建立其端到端功能的关键设计，因此对象检测不需要手工制作的NMS（非最大抑制）方法来删除重复检测。这种端到端的签名对于DETR的多功能性很重要，并且已将其推广到广泛的视觉问题，包括实例/语义分割，人体姿势估计以及基于点云/多视图的检测，但是，我们注意到，由于分配为正样本的查询太少，因此一对一的匹配显着降低了阳性样品的训练效率。本文提出了一种基于混合匹配方案的简单而有效的方法，该方法将原始的一对一匹配分支与辅助查询结合在一起，这些查询在训练过程中使用一对一的匹配损失。该混合策略已被证明可显着提高训练效率并提高准确性。在推断中，仅使用原始的一对一匹配分支，从而维持端到端的优点和相同的DETR推断效率。该方法命名为$ \ MATHCAL {H} $ - DETR，它表明可以在各种视觉任务中始终如一地改进各种代表性的DITR方法，包括可变形，3DDER/PETRV2，PETR和TRANDRACK， ，其他。代码将在以下网址提供：https：//github.com/hdetr

基于模型的离线优化通过动态感知政策为策略学习和分布外概括提供了新的观点，在该策略中，学会的政策可以适应培训阶段列举的不同动态。但是，由于离线设置下的限制，学到的模型无法很好地模仿真实的动态，以支持可靠的分发勘探，这仍然阻碍了政策以良好的概括。为了缩小差距，先前的作品大致集成了随机初始化的模型，以更好地近似实际动力学。但是，这种做法是昂贵且效率低下的，并且无法保证学识渊博的模型可以近似真正的动态，我们在本文中命名了覆盖性。我们通过生成具有可证明的能力以有效且可控制的方式覆盖真实动态的模型来积极解决这个问题。为此，我们根据动力学下的策略占用，为动态模型设计一个距离度量，并提出了一种算法来生成模型，以优化其对真实动力学的覆盖范围。我们对模型生成过程进行了理论分析，并证明我们的算法可以提供增强的覆盖性。作为一项下游任务，我们以较小或没有保守的惩罚训练动态感知政策，实验表明我们的算法在现有的离线RL基准测试中优于先前的离线方法。我们还发现，通过我们的方法学到的政策具有更好的零转移性能，这意味着它们的概括更好。

基于变压器的语言模型能够生成流利的文本，并在各种自然语言生成任务中有效地适应。但是，已证明在大型未标记的网络文本语料库中鉴定的语言模型已被证明会遭受堕落的有毒内容和社会偏见行为的损害，从而阻碍了他们的安全部署。提出了各种排毒方法来减轻语言模型的毒性；但是，这些方法是在包含与性别，种族或宗教相关的特定社会身份的提示条件下进行排毒语言模型的。在这项研究中，我们提出了增强氧化。一种基于强化学习的方法，用于降低语言模型中的毒性。我们应对语言模型中的安全性挑战，并提出了一种新的奖励模型，该模型能够检测有毒内容并减轻对毒性预测中社会身份的意外偏见。该实验表明，用于语言模型排毒的增强方法化方法优于自动评估指标中现有的排毒方法，这表明我们在语言模型排毒中的方法能力和对生成内容中社会认同的意外偏见的能力较小。

This paper illustrates the technologies of user next intent prediction with a concept knowledge graph. The system has been deployed on the Web at Alipay, serving more than 100 million daily active users. Specifically, we propose AlipayKG to explicitly characterize user intent, which is an offline concept knowledge graph in the Life-Service domain modeling the historical behaviors of users, the rich content interacted by users and the relations between them. We further introduce a Transformer-based model which integrates expert rules from the knowledge graph to infer the online user's next intent. Experimental results demonstrate that the proposed system can effectively enhance the performance of the downstream tasks while retaining explainability.

Blind watermarking provides powerful evidence for copyright protection, image authentication, and tampering identification. However, it remains a challenge to design a watermarking model with high imperceptibility and robustness against strong noise attacks. To resolve this issue, we present a framework Combining the Invertible and Non-invertible (CIN) mechanisms. The CIN is composed of the invertible part to achieve high imperceptibility and the non-invertible part to strengthen the robustness against strong noise attacks. For the invertible part, we develop a diffusion and extraction module (DEM) and a fusion and split module (FSM) to embed and extract watermarks symmetrically in an invertible way. For the non-invertible part, we introduce a non-invertible attention-based module (NIAM) and the noise-specific selection module (NSM) to solve the asymmetric extraction under a strong noise attack. Extensive experiments demonstrate that our framework outperforms the current state-of-the-art methods of imperceptibility and robustness significantly. Our framework can achieve an average of 99.99% accuracy and 67.66 dB PSNR under noise-free conditions, while 96.64% and 39.28 dB combined strong noise attacks. The code will be available in https://github.com/rmpku/CIN.

Most research on task oriented dialog modeling is based on written text input. However, users interact with practical dialog systems often using speech as input. Typically, systems convert speech into text using an Automatic Speech Recognition (ASR) system, introducing errors. Furthermore, these systems do not address the differences in written and spoken language. The research on this topic is stymied by the lack of a public corpus. Motivated by these considerations, our goal in hosting the speech-aware dialog state tracking challenge was to create a public corpus or task which can be used to investigate the performance gap between the written and spoken forms of input, develop models that could alleviate this gap, and establish whether Text-to-Speech-based (TTS) systems is a reasonable surrogate to the more-labor intensive human data collection. We created three spoken versions of the popular written-domain MultiWoz task -- (a) TTS-Verbatim: written user inputs were converted into speech waveforms using a TTS system, (b) Human-Verbatim: humans spoke the user inputs verbatim, and (c) Human-paraphrased: humans paraphrased the user inputs. Additionally, we provided different forms of ASR output to encourage wider participation from teams that may not have access to state-of-the-art ASR systems. These included ASR transcripts, word time stamps, and latent representations of the audio (audio encoder outputs). In this paper, we describe the corpus, report results from participating teams, provide preliminary analyses of their results, and summarize the current state-of-the-art in this domain.

Lobster eye telescopes are ideal monitors to detect X-ray transients, because they could observe celestial objects over a wide field of view in X-ray band. However, images obtained by lobster eye telescopes are modified by their unique point spread functions, making it hard to design a high efficiency target detection algorithm. In this paper, we integrate several machine learning algorithms to build a target detection framework for data obtained by lobster eye telescopes. Our framework would firstly generate two 2D images with different pixel scales according to positions of photons on the detector. Then an algorithm based on morphological operations and two neural networks would be used to detect candidates of celestial objects with different flux from these 2D images. At last, a random forest algorithm will be used to pick up final detection results from candidates obtained by previous steps. Tested with simulated data of the Wide-field X-ray Telescope onboard the Einstein Probe, our detection framework could achieve over 94% purity and over 90% completeness for targets with flux more than 3 mCrab (9.6 * 10-11 erg/cm2/s) and more than 94% purity and moderate completeness for targets with lower flux at acceptable time cost. The framework proposed in this paper could be used as references for data processing methods developed for other lobster eye X-ray telescopes.